Izimiso ze-photoacoustic imaging

Izimiso ze-photoacoustic imaging

I-Photoacoustic Imaging (PAI) iyindlela yokucabanga yezokwelapha ehlanganisayoopticskanye nama-acoustics ukukhiqiza amasignali e-ultrasonic usebenzisa ukuxhumana kweukukhanyangezicubu ukuthola izithombe zethishu ezinokulungiswa okuphezulu. Isetshenziswa kabanzi emikhakheni ye-biomedical, ikakhulukazi ekutholeni isimila, izithombe zemithambo, izithombe zesikhumba neminye imikhakha.

Isimiso:
1. Ukumuncwa okukhanyayo nokunwetshwa kokushisa: - I-Photoacoustic imaging isebenzisa umphumela wokushisa okhiqizwa ukumuncwa ukukhanya. Amangqamuzana e-pigment esicutshini (isb., i-hemoglobin, i-melanin) amunca ama-photon (ngokuvamile acishe abe ukukhanya kwe-infrared), aguqulelwe abe amandla okushisa, abangele amazinga okushisa endawo akhuphuke.
2. Ukwanda okushisayo kubangela i-ultrasound: – Ukukhuphuka kwezinga lokushisa kuholela ekwandeni okushisayo kwezicubu, okukhiqiza amaza omfutho (okungukuthi i-ultrasound).
3. Ukutholwa kwe-Ultrasonic: – Amaza e-ultrasonic akhiqizwayo asakazeka ngaphakathi kwethishu, futhi lezi zimpawu zitholwa futhi zirekhodwe izinzwa ze-ultrasonic (njengama-ultrasonic probes).
4. Ukwakhiwa kabusha kwesithombe: isignali ye-ultrasonic eqoqwe ibalwa futhi icutshungulwe ukuze kwakhiwe kabusha isakhiwo nomsebenzi wesithombe sethishu, esinganikeza izici zokumuncwa kwe-optical yezicubu. Izinzuzo zesithombe se-photoacoustic: Ukugqama okuphezulu: Ukuthwebula kwesithombe kuncike ezicini zokumunca ukukhanya kwezicubu, futhi izicubu ezihlukene (njengegazi, amafutha, imisipha, njll.) zinamakhono ahlukene okumunca ukukhanya, ngakho-ke kunganikeza izithombe ezinomehluko ophezulu. Ukulungiswa okuphezulu: Ngokusebenzisa ukulungiswa okuphezulu kwendawo kwe-ultrasound, imaging photoacoustic ingafinyelela ukunemba kwe-millimeter noma ngisho ne-sub-millimeter yokunemba kwesithombe. Akuna-invasive: I-Photoacoustic imaging ayihlaseli, ukukhanya nomsindo ngeke kubangele ukulimala kwezicubu, kulungele kakhulu ukuxilongwa kwezokwelapha komuntu. Ikhono lokucabanga elijulile: Uma kuqhathaniswa ne-imaging yendabuko ye-optical, imaging photoacoustic ingangena ngamasentimitha ambalwa ngaphansi kwesikhumba, esifanele ukuthwebula kwezicubu ezijulile.

Isicelo:
1. I-Vascular imaging: - I-Photoacoustic imaging ingakwazi ukubona izici ezimunca ukukhanya ze-hemoglobin egazini, ngakho-ke ingabonisa ngokunembile ukwakheka nesimo se-oksijini semithambo yegazi ukuze kuqashwe i-microcirculation kanye nokwahlulela izifo.
2. Ukutholwa kwesimila: – I-Angiogenesis ezicutshini zesimila ngokuvamile iba kuningi ngokwedlulele, futhi imaging photoacoustic ingasiza ukutholwa kusenesikhathi kwamathumba ngokuthola ukungahambi kahle kwesakhiwo semithambo.
3. I-imaging esebenzayo: - I-Photoacoustic imaging ingahlola ukutholakala komoyampilo kwezicubu ngokuthola ukugcwala kwe-oxygenation ne-deoxyhemoglobin ezicutshini, okubaluleke kakhulu ekuqaphelweni kokusebenza kwezifo ezinjengomdlavuza nesifo senhliziyo.
4. Ukuthwebula isithombe sesikhumba: – Ngenxa yokuthi i-photoacoustic imaging izwela kakhulu ezicutshini ezingaphandle, ifaneleka ukuhlonzwa kusenesikhathi komdlavuza wesikhumba nokuhlaziywa kokungajwayelekile kwesikhumba.
5. Ukuthwebula izithombe zobuchopho: I-Photoacoustic imaging ingathola ulwazi lokugeleza kwegazi lobuchopho ngendlela engahlaseli ukuze kuhlolwe izifo zobuchopho ezifana nokushaywa unhlangothi kanye nesifo sokuwa.

Izinselelo nezikhombisi-ndlela zokuthuthukiswa kwe-photoacoustic imaging:
Umthombo wokukhanyaukukhetha: Ukungena okukhanyayo kwamaza ahlukene kuhlukile, indlela yokukhetha ukulungiswa kwebhalansi ye-wavelength efanele kanye nokujula kokungena kuyinselele. Ukucutshungulwa kwesiginali: Ukutholwa kanye nokucutshungulwa kwamasignali e-ultrasonic kudinga ama-algorithms anesivinini esikhulu futhi anembile, futhi ukuthuthukiswa kobuchwepheshe bokwakha kabusha izithombe nakho kubalulekile. I-Multimodal imaging: I-Photoacoustic imaging ingahlanganiswa nezinye izindlela zokucabanga (ezifana ne-MRI, CT, imaging ultrasound) ukuze kunikezwe ulwazi olubanzi lwe-biomedical.

I-Photoacoustic imaging ubuchwepheshe obusha obusebenzayo be-biomedical imaging, obunezici zokugqama okuphezulu, ukulungiswa okuphezulu nokungahlaseli. Ngokuthuthuka kobuchwepheshe, imaging photoacoustic inamathemba abanzi okusebenza ekuxilongweni kwezokwelapha, ucwaningo oluyisisekelo lwebhayoloji, ukuthuthukiswa kwezidakamizwa neminye imikhakha.