Izimiso zokuthwebula izithombe ze-photoacoustic

Izimiso zokuthwebula izithombe ze-photoacoustic

I-Photoacoustic Imaging (PAI) iyindlela yokuthwebula izithombe yezokwelapha ehlanganisaizibuko zokukhanyakanye nemisindo yomsindo ukukhiqiza izimpawu ze-ultrasonic kusetshenziswa ukusebenzisana kweukukhanyangezicubu ukuthola izithombe zezicubu ezisezingeni eliphezulu. Isetshenziswa kabanzi emikhakheni yezokwelapha, ikakhulukazi ekutholakaleni kwesimila, ekuthathweni kwezithombe zemithambo yegazi, ekuthathweni kwezithombe zesikhumba nakwezinye izinkambu.

Isimiso:
1. Ukumuncwa kokukhanya kanye nokwanda kokushisa: – Ukuthwebula nge-photoacoustic kusebenzisa umphumela wokushisa okhiqizwa ukumuncwa kokukhanya. Ama-molecule e-pigment esicutshini (isb., i-hemoglobin, i-melanin) amunca ama-photon (ngokuvamile ukukhanya okuseduze ne-infrared), aguqulwa abe amandla okushisa, okubangela ukuba amazinga okushisa endawo akhuphuke.
2. Ukwanda kokushisa kubangela i-ultrasound: – Ukwenyuka kokushisa kuholela ekwandeni okuncane kokushisa kwezicubu, okukhiqiza amagagasi okucindezela (okungukuthi i-ultrasound).
3. Ukutholwa kwe-Ultrasonic: – Amagagasi e-ultrasonic akhiqizwayo asakazeka ngaphakathi kwezicubu, futhi lezi zimpawu kamuva zamukelwa futhi ziqoshwe yizinzwa ze-ultrasonic (njengezivivinyo ze-ultrasonic).
4. Ukwakhiwa kabusha kwesithombe: isignali ye-ultrasonic eqoqwe iyabalwa futhi icutshungulwe ukuze kwakhiwe kabusha isakhiwo kanye nesithombe somsebenzi wezicubu, okunganikeza izici zokumunca ezibonakalayo zezicubu. Izinzuzo zesithombe se-photoacoustic: Umehluko omkhulu: Isithombe se-photoacoustic sincike ezicini zokumunca ukukhanya kwezicubu, futhi izicubu ezahlukene (njengegazi, amafutha, imisipha, njll.) zinamakhono ahlukene okumunca ukukhanya, ngakho-ke zinganikeza izithombe ezihluke kakhulu. Ukulungiswa okuphezulu: Ngokusebenzisa isinqumo esiphezulu sendawo se-ultrasound, isithombe se-photoacoustic singafinyelela ukunemba kwesithombe se-millimeter noma ngisho ne-sub-millimeter. Okungahlaseli: Isithombe se-photoacoustic asihlaseli, ukukhanya nomsindo ngeke kubangele ukulimala kwezicubu, kufaneleka kakhulu ekuxilongweni kwezokwelapha kwabantu. Amandla okuthwebula izithombe ezijulile: Uma kuqhathaniswa nesithombe se-optical esivamile, isithombe se-photoacoustic singangena ngamasentimitha ambalwa ngaphansi kwesikhumba, okufanelekela izithombe zezicubu ezijulile.

Isicelo:
1. Ukuthwebula izithombe zemithambo yegazi: – Ukuthwebula izithombe ze-photoacoustic kungathola izakhiwo ezimunca ukukhanya kwe-hemoglobin egazini, ngakho-ke kungabonisa ngokunembile isakhiwo kanye nesimo sokufakwa komoya-mpilo emithanjeni yegazi ukuze kuqashwe ukugeleza kwegazi okuncane kanye nokwahlulela izifo.
2. Ukutholwa kwezicubu: – I-Angiogenesis ezicutshini zesimila ivame ukuba ningi kakhulu, futhi izithombe ze-photoacoustic zingasiza ekutholakaleni kwangaphambi kwesikhathi kwezimila ngokuthola ukukhubazeka esakhiweni semithambo yegazi.
3. Ukuthwebula izithombe ezisebenzayo: – Ukuthwebula izithombe nge-photoacoustic kungahlola ukuhlinzekwa komoya-mpilo kwezicubu ngokuthola ukugcwala komoya-mpilo kanye ne-deoxyhemoglobin ezicutshini, okubaluleke kakhulu ekuqapheni ukusebenza kwezifo ezifana nomdlavuza kanye nesifo senhliziyo.
4. Ukuthwebula izithombe zesikhumba: – Ngenxa yokuthi ukuthwebula izithombe ze-photoacoustic kuzwela kakhulu ezicutshini ezingajulile, kufanelekile ekutholakaleni komdlavuza wesikhumba kusenesikhathi kanye nokuhlaziywa kweziphambeko zesikhumba.
5. Ukuthwebula izithombe zobuchopho: Ukuthwebula izithombe ze-photoacoustic kungathola ulwazi lokugeleza kwegazi lobuchopho ngendlela engahlaseli ukuze kufundwe izifo zobuchopho ezifana nesifo sohlangothi kanye nesifo sokuwa.

Izinselele kanye nezinkomba zokuthuthukiswa kwezithombe ze-photoacoustic:
Umthombo wokukhanyaukukhetha: Ukungena kokukhanya kwama-wavelength ahlukene kuhlukile, indlela yokukhetha isixazululo sebhalansi ye-wavelength efanele kanye nokujula kokungena kuyinselele. Ukucubungula isignali: Ukutholwa kanye nokucubungula izignali ze-ultrasonic kudinga ama-algorithms asheshayo futhi anembile, kanye nokuthuthukiswa kobuchwepheshe bokwakha kabusha izithombe nakho kubalulekile. Ukuthwebula izithombe ze-Multimodal: Ukuthwebula izithombe ze-photoacoustic kungahlanganiswa nezinye izindlela zokuthwebula izithombe (njenge-MRI, i-CT, i-ultrasound imaging) ukuze kunikezwe ulwazi oluphelele lwezokwelapha.

Ukuthwebula izithombe nge-Photoacoustic ubuchwepheshe obusha nobunemisebenzi eminingi bokuthwebula izithombe nge-biomedical, obunezici zokungafani okuphezulu, ukucaca okuphezulu kanye nokungahlaseli. Ngokuthuthuka kobuchwepheshe, ukuthwebula izithombe nge-photoacoustic kunamathuba amaningi okusetshenziswa ekuxilongweni kwezokwelapha, ucwaningo oluyisisekelo lwebhayoloji, ukuthuthukiswa kwemithi kanye neminye imikhakha.